Euflexxa

EUFLEXXA is a gel-like, elastic, sterile product containing natural, highly purified hyaluronan, also known as sodium hyaluronate.

Hyaluronan is a substance found naturally in the body and is present in particularly high amounts in joint tissues and the synovial fluid (the fluid that fills the joints). Hyaluronan acts as a lubricant and shock absorber for the joints and allows the cartilage, the protective surfaces of your bones, to glide over each other smoothly. This helps the joints to work properly.

Osteoarthritis is a condition that involves the wearing down of cartilage and a reduction in the amount of hyaluronan in the joint fluid and tissues. In osteoarthritis, the quality of the hyaluronan in the joints may be reduced and there may not be enough hyaluronan to help the joints work properly.

Euflexxa is used to relieve joint pain caused by osteoarthritis of the knee, hip, shoulder and ankle.
It is an injectable synthetic version of hyaluronan, the key ingredient of synovial fluid found naturally in the joint space. With osteoarthritis, the normal synovial fluid becomes dysfunctional, leading to friction and inflammation. By lubricating the joint, Euflexxa may reduce pain and reinstate joint flexibility and mobility, thereby enhancing the overall quality of life for patients.

EUFLEXXA is used to relieve joint pain caused by osteoarthritis of the knee joint or other synovial joints. EUFLEXXA reduces pain in the affected joint by helping to lubricate the joint, allowing for greater joint mobility and flexibility.

ARE THERE ANY REASONS WHY YOU SHOULD NOT TAKE EUFLEXXA?

• Previous allergic reaction to EUFLEXXA or hyaluronan products
• Joint infection, skin diseases or infections around the injection site
• EUFLEXXA has not been tested in pregnant women or women who are nursing. You should tell your doctor if you think you are pregnant or if you are nursing a child.

The safety and effectiveness of EUFLEXXA have not been shown in children under 18 years of age.

EUFLEXXA must be administered by doctor/qualified medical personnel.

EUFLEXXA comes in pre-filled syringes containing 2 mL of product. EUFLEXXA is given by injection directly into the affected knee joint or other synovial joint.

Your doctor will give you your injection into your affected knee joint or other affected synovial joints once a week, for a total of three injections.

Euflexxa treatment is administered over three appointments, 2 weeks apart. At each appointment the patient will receive a CT guided injection of Euflexxa in a sterile environment, into the affected joint.Patients typically see greatest results on completion of the 3 injections, with benefits lasting up to 6 months. If required, the treatment can be performed twice a year.

Your doctor has weighed the risks of using this product against the benefits they expect it will have for you. Ask your doctor any questions you may have.

Tell your doctor if you notice any of the following after you are given EUFLEXXA:

• Itching, redness, swelling at the injection site. Application of ice to the treated joint may help to relieve these symptoms. These symptoms are usually short-lived.
• feeling sick (nausea)
• feeling tired (fatigue)
• tenderness
• back pain
• skin irritation
• increased blood pressure
• burning, itching, and/or tingling sensation

Tell your doctor if you notice anything that is making you feel unwell.

Anyone who has had a previous allergic reaction to Euflexxa or hyaluronan products.
Anyone who has a joint infection, skin diseases or infections around the injection site.